Naloxone, commonly known under the brand name Narcan, is a medication that rapidly reverses the effects of an opioid overdose. Until this year, all forms of naloxone had been designated as prescription-only. After hearing from an expert advisory panel, the U.S. Food and Drug Administration (FDA) approved the sale of over-the-counter naloxone hydrocholoride nasal spray nationwide in March. The decision removes a critical access barrier to the life-saving treatment, thereby reducing overdose deaths and the associated stigma. Implementation will be ongoing in the coming months with pending information on the cost of the medication. To learn more, see the news release from the FDA.