Genetic Testing Shows Promise for Medication Selection for MDD

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About Mental Illness

A mental illness is a medical condition that disrupts a person’s thinking, feeling, mood, ability to relate to others and daily functioning.

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Recovery from serious mental illness is not only possible, but for many people living with mental illness today, probable. The notion of recovery involves a variety of perspectives.

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Antidepressants are often one of the first treatment approaches for individuals with depressive disorders, but many struggle with side effects and finding the appropriate medication or dosage. Recent findings from a randomized controlled trial indicate that pharmacogenomic testing could be helpful in medication selection for patients with major depressive disorder (MDD). Participants who were prescribed medication and dosage based on their genetic testing results were less likely to present drug-gene interactions and more likely to experience remission over 24 weeks. However, the researchers note that the participants’ improvements are not significant compared to the control group at the the 24-week mark. Pharmacogenic testing is an evolving field, and more research is needed to fully understand its efficacy for individuals with mental health conditions. To learn more, see the study in JAMA.

About Mental Illness

A mental illness is a medical condition that disrupts a person’s thinking, feeling, mood, ability to relate to others and daily functioning.

What is Recovery

Recovery from serious mental illness is not only possible, but for many people living with mental illness today, probable. The notion of recovery involves a variety of perspectives.

We’re Here to Listen

In Crisis?

You can chat one-to-one online at:
www.Foundation2CrisisChat.org
Online & texting chats are available from 9am-3pm M-F. All contacts are confidential.

Call the NAMI Helpline at

1-800-950-NAMI (6264)

Or in a crisis, text “NAMI” to 741741

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